General Cell Lines and Cell Cultures
Sartorius Human Multi Ab Internalization
No wash protocol- fast easy antibody-labeling method optimal for screening antibody internalization.High throughput evaluation of antibody internalization- Assay designed to measure internalization of a large number of antibodies in 96- and 384-well plate formats using 10 L of cells and 10 L of labeled antibody kit .Simultaneously measure antibody internalization cell specificity and cell health within the same well.PrincipleAntibodies are easily labeled with Intellicyt Antibody Internalization Reagent a novel pH sensitive dye.
ATCC Vaginal Epithelial Cell Growth Kit
Vaginal Epithelial Cell Growth Kit contains components that when added to Vaginal Epithelial Cell Basal Medium (ATCC PCS-480-030) create a complete ATCC Primary Cell Solutions culture environment for vaginal epithelial cells derived from normal human vaginal tissue (eg, Primary Vaginal Epithelial Cells, Normal, Human, ATCC PCS-480-010). The serum-free medium formulation can support normal vaginal cell morphology and promote rapid growth and proliferation. No feeder layers, extracellular matrix proteins, or other substrates are required.
Biochain Institute Inc Paraffin Tissue Section - Human Gallbladder Tumor: Adenocarcinoma, Poorly Differentiated, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Acinetobacter baumannii
Acinetobacter baumannii strain Vitek #109234 [API 8310086, NSB 4221] is a clinical specimen isolated from ear pus. This bacterial culture can be used as a quality control strain for the VITEK 2 GN Comprehensive QC Set.
Eurofins Discoverx Ready-to-Assay GPBA Bile Acid Receptor Frozen Cells, 2 Vials of Cells. (HTS238LRTA)
The Ready-to-Assay GPBA Bile Acid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. lithocholic acid, other bile acids) based activation of GPBAR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GPBAR1 alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of GPBAR1, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC SW948; Colon Adenocarcinoma; Human (Homo sapiens)
SW948 is a cell line exhibiting epithelial morphology from the colon of a White, 81-year-old, female patient with adenocarcinoma colorectal Dukes' type C, grade III. This cell line was deposited by A Leibovitz.
Eurofins Discoverx PathHunter CHO-K1 mGPR91 (SUCNR1) β-Arrestin Cell Pool, 2 vials. (93-0589P2)
The PathHunter mGPR91 (SUCNR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. succinate) based activation of mGPR91 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGPR91 and EA-tagged β-Arrestin-2. Activation of mGPR91 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Abcam CGP 52432 (mM/ml), GABAB antagonist, 10MM_ML
MW 384.2 Da, Purity >99%. Potent, selective GABAB antagonist (IC50 = 85 nM). Soluble in 1 ml water to give specified mM/ml concentration.
The product is subject to the following: Abcam Restricted Use Statement
ACROBiosystems HEK293/Human SORT1 Stable Cell Line
The Sortilin is a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer.
Eurofins Discoverx Ready-to-Assay FFA3/GPR41 Free Fatty Acid Receptor Frozen Cells, 2 Vials of Cells. (HTS135RTA)
The Ready-to-Assay FFA3/GPR41 Free Fatty Acid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. free fatty acids) based activation of FFAR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR3 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of FFAR3, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC C1498; Acute Myeloid Leukemia; Mouse (Mus musculus)
C1498 are lymphoblasts that were isolated from a female mouse with acute myeloid leukemia. It has applications in immune system disorder research.
ATCC TransfeX Transfection Reagent
TransfeX Transfection Reagent is a biochemical method for transfection suitable for a number of mammalian cell types. TransfeX Transfection Reagent provides high efficiency with low cell mortality.
ATCC 293; Embryonic Kidney; Human (Homo sapiens)
293 [HEK-293] is a cell line exhibiting epithelial morphology that was isolated from the kidney of a human embryo. This cell line can be used in industrial biotechnology and toxicology research. It has applications in efficacy testing and viruscide testing.
ATCC WEHI-231; B Lymphocyte; Mouse (Mus musculus)
WEHI-231 is a B lymphocyte cell that was isolated from a mouse. This cell line was deposited by NL Warner and L Lanier. WEHI-231 can be used in immunology research.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Kidney, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.